[Energy distribution and ionic selectivity of the bacterial potassium channel].

An explanation for the ionic selectivity of the bacterial potassium channel K(CS)A is offered, which is based on a comparison of energy interactions of lithium, sodium, and potassium cations with the atoms of the selective filter of an protein pore. Using quantum-chemical calculations, the presence of a deeper potential hole for potassium ions was discovered, which explains the energy preferableness in their permeability. It has been shown that the traditional methods of force field AMBER, CHARMM, OPLS in reference parametrization and also at their partial reparametrization give incorrect ratings of energy distribution of ions in the channel.

[Energy levels and ion wave functions in gramicidin channels].

A model study of the motion of Na+ ions in the cavity of membrane gramicidin channels was performed by the methods of quantum mechanics. An approximation of the distribution of the electrostatic potential along the channel axis, determined by charges on the atoms of the gramicidin A molecule, was obtained. The energy distribution and the wave functions for the stationary states of the ions were determined.

[The content of free amino acids in the blood of children with intellectual disorders].

Measurements of the concentrations of free amino acids in blood of children with intellect deficiency whose parents suffered from alcoholism showed an imbalance of some amino acids.

[Ultrasonic and x-ray studies in urolithiasis].

Ultrasonic and x-ray investigations were performed in 208 urolithiasis suspects. Concrements were diagnosed in 156 of them. X-rays failed to find concrements in 25 patients out of 128 with calyceal concrements diagnosed ultrasonically because of the concrements' small size, their x-ray negativity and ultrasonic hyperdiagnosis.