Publications by authors named "V Kuzhandai Velu"
Purpose Of Review: Natural killer (NK) cells are integral components of the innate immune system, serving a vital function in eliminating virally infected cells. This review highlights the significance of CXCR5+ NK cells in the context of chronic HIV/SIV infection and viral control.
Recent Findings: Controlled HIV/SHIV infection results in a substantial increase in the population of CXCR5+ NK cells within the B-cell follicles of secondary lymphoid organs (SLOs).
Correction: Attrition in serum anti-DENV antibodies correlates with high anti-SARS-CoV-2 IgG levels and low DENV positivity in mosquito vectors-Findings from a state-wide cluster-randomized community-based study in Tamil Nadu, India.
PLOS Glob Public Health
December 2024
[This corrects the article DOI: 10.1371/journal.pgph.
View Article and Find Full Text PDFAttrition in serum anti-DENV antibodies correlates with high anti-SARS-CoV-2 IgG levels and low DENV positivity in mosquito vectors-Findings from a state-wide cluster-randomized community-based study in Tamil Nadu, India.
PLOS Glob Public Health
November 2024
The decline in dengue incidence and/or prevalence during the COVID-19 pandemic (2020-22) appears to be attributed to reduced treatment-seeking rates, under-reporting, misdiagnosis, disrupted health services and reduced exposure to mosquito vectors due to prevailing lockdowns. There is limited scientific data on dengue virus (DENV) disease during the COVID-19 pandemic. Here, we conducted a community-based, cross-sectional, cluster-randomized survey to assess anti-DENV and anti-SARS-CoV-2 seroprevalence, and also estimated the spatial distribution of DENV-positive aedine mosquito vectors during the COVID-19 pandemic across all the 38 districts of Tamil Nadu, India.
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- Ovarian hormones influence the immune system in the female genital tract (FGT), and this study explores how the menstrual cycle affects HIV target cell levels and memory CD4 T cells.
- Researchers collected endocervical cells from 105 healthy women and analyzed different CD4 T cell subsets, focusing on their distribution and function during the follicular and luteal phases of the menstrual cycle.
- Results showed that certain CD4 T cell types were more prevalent in the follicular phase, which may increase susceptibility to HIV, highlighting the dynamic changes in immune response linked to hormonal fluctuations throughout the menstrual cycle.
In December 2023, we observed a notable shift in the COVID-19 landscape, when JN.1 omicron emerged as the predominant SARS-CoV-2 variant with a 95% incidence. We characterized the clinical profile, and genetic changes in JN.
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