MODIFIED TREATMENT OF HEPATORENAL SYNDROME TYPE I DEPENDING ON THE STAGE OF ACUTE KIDNEY INJURY.

Hepatorenal syndrome is a severe complication of liver cirrhosis which is difficult to treat because of a very fast course and lack of adequate dosing recommendations due to the stage of the disease. In this study we aimed to refine the treatment of hepatorenal syndrome type I by modifying the dose of terlipressin, depending on the stage of acute kidney injury (AKI). Objective - to improve the treatment method of hepatorenal syndrome type I in patients with alcoholic liver cirrhosis by selecting the dose of terlipressin depending on the stage of acute kidney injury.

[Efficacy of application of colonic lavage for peritonitis of biliary genesis].

The species and quantitative composition of the bile microflora, peritoneal exudate, colonic cavity and mucosa was studied in 55 patients and in experiment on 17 mongrel dogs to estimate efficacy of application of colonosanation method in treatment of an acute peritonitis of biliary origin. It was established that in occurrence of peritonitis of biliary origin the essential role play disorders of intestinal microbic landscape and his colonizing resistance. Application of elaborated method of colonosanation had permitted to a considerable extent to eliminate these disorders and to improve result of treatment of the patients.