On the Environmentally Friendly Synthesis of 2-Hydroxyethyl Furan-5-Carboxylic Acid (MHEF) and bis(2-Hydroxyethyl) Furan-2,5-Dicarboxylate (BHEF).

To better understand how the biocatalyzed depolymerization of polyesters works, model molecules are needed to develop activity assays and determine enzymatic kinetic parameters. In this communication the chemical synthesis and characterization of 2-hydroxyethyl furan-5-carboxylic acid and bis(2-hydroxyethyl) furan-2,5-dicarboxylates as potential model molecules to further study the enzymatic depolymerization of poly(ethylene furanoate) was investigated.

bneR: A collaborative workflow for air pollution exposure modeling and uncertainty characterization using the Bayesian Nonparametric Ensemble.

Background: Air pollution is a major public health threat globally. Health studies, regulatory actions, and policy evaluations typically rely on air pollutant concentrations from single exposure models, assuming accurate estimations and ignoring related uncertainty. We developed a modeling framework, bneR, to apply the Bayesian Nonparametric Ensemble (BNE) prediction model that combines existing exposure models as inputs to provide air pollution estimates and their spatio-temporal uncertainty.

Unveiling the trends: Growing cancer and venous thromboembolism mortality in older adults in the United States, 1999-2020.

Background: While cancer mortality rates in the United States (U.S.) have decreased due to advances in chemotherapy, older adults with cancer face an elevated risk of venous thromboembolism (VTE).

Development of Mobile Application Based System for Improving Population Based Cancer Screening by Community Health Workers.

Objective: Cancer remains a leading cause of morbidity and mortality globally, with India experiencing a significant cancer burden. Effective population-based cancer screening is crucial for early detection and reduction of cancer-related deaths. This study aims to develop a mobile application-based Cancer Screening and Surveillance System (CSMS) to enhance the efficiency and effectiveness of population-based cancer screening by community health workers (CHWs).

Pharmacophore-based virtual screening of the chromone derivatives as potential therapeutic for Alzheimer's disease.

Alzheimer's disease is one of the most complex neurological disorders and millions of people are suffering from this disease all over the world. In the past two decades acetylcholinesterase (AChE) has been the most explored pathological hallmark. The generation of potent AChE inhibitors has grown as a rapid pathological tool for the efficacious treatment of the disease.