Publications by authors named "V Kotov S"

Verrucae vulgaris are infectious keratotic lesions caused by the human papillomavirus (HPV), frequently impairing an individual's quality of life, mainly when situated on the facial region. Verruca vulgaris constitutes a prevalent dermatological issue with diverse repercussions for those affected. The interaction among HPV, the immune system, and treatment methods requires a sophisticated comprehension of this illness.

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Stimuli-responsive supramolecular assemblies have recently gained extensive attention in the biomedical field. Research focusing mainly on bioinspired functional supramolecular materials has shown great promise for potential drug delivery applications. Such materials can be engineered into 'smart' materials by utilizing various external stimuli such as pH, heat, light, and magnetic fields.

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Objective: This study aimed to formulate leaf extract (MAE) loaded solid lipid nanoparticles (SLNs) and investigate its cytotoxic potential using MDA-MB231 cell line.

Significance: SLNs can protect MAE from degradation, enhance cytotoxicity potential, and making them suitable for various therapeutic areas.

Methods: SLNs were developed using high-pressure homogenization method, and the formulations were optimized based on particle size, zeta potential, % entrapment efficiency (EE), and % cumulative drug release (CDR).

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Objectives: This study aimed to report the findings of comprehensive weekly quality audit of radiotherapy procedures conducted at our institute, assessing various domains including clinical notes, contour delineation, treatment planning, prescription accuracy, patient-specific quality assurance, and treatment set-up checks.

Material And Methods: The audit protocol, based on the Peer Review Audit Tool (PRAT) from the Royal Australian and New Zealand College of Radiologists, evaluated six critical parameters: clinical decisions, contours, treatment prescriptions, plan evaluation, plan quality assurance, and daily treatment set-ups. Patients were assessed for changes categorized as no change, minor change, or major change.

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Introduction:  In modern healthcare, computed tomography (CT) is essential for diagnosing a wide range of medical conditions, particularly in emergency settings where timely evaluation of critical areas such as the brain, thorax, abdomen, and pelvis is crucial. However, the increasing reliance on provisional reports generated by postgraduates during on-call hours introduces challenges, as discrepancies often arise between these initial reports and final assessments by senior radiologists. These discrepancies can affect patient outcomes, particularly in complex cases, underscoring the need for studies that evaluate the patterns and clinical relevance of discrepancies across multiple CT modalities.

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