SARS-CoV-2 utilizes the angiotensin-converting enzyme 2 (ACE2) receptors located on membranes to enter host cells. Nevertheless, the gene primarily encodes for a zinc metalloproteinase, which is a part of the renin-angiotensin system (RAS). ACE2 downregulation results in the deregulation of RAS in favor of pro-fibrosis, pro-apoptosis, oxidative stress, pro-inflammation, aldosterone production and release, and blood vessel contraction axis.
View Article and Find Full Text PDFIntroduction: Weight regain is a serious issue after bariatric surgery. Using banding for one anastomotic gastric bypass prevents weight regain, but carries the risk of band erosion. The combination of bariatric procedures and fundoplication for patients without hiatal hernia probably prevents weight regain.
View Article and Find Full Text PDFObjective: To study and analyze the working time distribution of general practitioners at the outpatient appointment in polyclinics of Karaganda, Kazakhstan.
Materials And Methods: The time spent by the general practitioner on all activities was studied by the timing method.
Results: a) general practitioners spend a great part of working time for the documentation and organizational measures; therefore, they spend less time for patients; b) it is necessary to maximally unload the doctor from working with documentation.
The inaccessibility of global university ratings for national universities is an urgent problem for many developing countries, including the Republic of Kazakhstan. This forces us to look for effective approaches that encourage national universities to increase their competitiveness and strive to enter global university rankings. Since one of the key components of global ratings is educational activity and the quality of the health personnel training is of particular value to the national health system, the aim of our study was to develop a national rating system for the educational activities of medical universities and evaluate its application in the national health system.
View Article and Find Full Text PDFGeorgian Med News
February 2020
Key indicators of performance (KPI) can be used to show the contribution of each employee or department/department to productivity in areas where quality or effectiveness can be measured. Performance indicators are usually agreed at the national or local level. When choosing a performance indicator for a nursing service, an analysis of the recommendations for testing effectiveness was required.
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