studies of designed thiadiazole derivatives as retinoic acid receptor-alpha (RAR-α) inhibitors for potential contraceptive application.

Retinoic acid receptors (RARs) are a class of nuclear receptors that play an important role in spermatogenesis. Blocking RAR-α activity is an effective method of contraception. In this study, we used methods to design and evaluate new thiadiazole-based RAR-α antagonists.

Unveiling a growth temperature-dependent ultra-sensitive tetragonal scheelite BiVO thin film-based gas sensor for ammonia volatilization at room temperature.

Ammonia (NH) vapour is considered as a hazardous volatile, which has the potential to cause health concerns in humans. Exposure to NH can lead to potentially fatal, severe burn injuries to human eyes, can cause encephalopathy, and also affects various physiological systems, including the liver, the kidneys and the immune system. Due to these prime factors, the advancement of chemi-resistive ammonia gas sensors at room temperature has drawn considerable attention among researchers.

From prescription to pollution: The ecological consequences of NSAIDs in aquatic ecosystems.

Nonsteroidal anti-inflammatory drugs are widely utilised to alleviate pain and reduce inflammation in both human and veterinary medicine. Despite their therapeutic benefits, NSAIDs pose environmental concerns due to their possible ecotoxicity. NSAIDs can enter aquatic ecosystems through wastewater discharge as it is very difficult to extract NSAIDs by conventional wastewater treatment, thus affecting aquatic life.