[The action of the artichoke (Cynara scolymus) on the male gonads in an experiment].

The gonadotropic effect of the Bulgarian preparation artichoke, developed on the basis of Cynara scolymus is studied. The preparation is used under the form of 50% aque emulsion, stabilized by emulgent Twin-80, in doses 35.70 and 150 mg/kg-1, 5 times weekly for 75 days.

[Experimental research on the chronic inhalational toxicity of chloracetophon].

The chronic inhalational toxicity of chloracetophon was studied on 24 albino Wistar rats, with concentrations 20 mg X m-3. The animal were exposed 4 hours/daily, 5 days/weekly, for 90 days. Integral, biochemical, histological and electron-microscopic methods were used for the evaluation of the toxic effect of the preparation.

[Occupational risk after repeated skin exposure to styrene].

The use of styrene in the production and processing of polymers, varnishes and paints is a prerequisite for a broad skin contact with the solvent, hence conditions for occupational effect on the workers, manifested with frequent contact toxic dermatitis. That determined the scope of this work, aiming at the specifying of the occupational risk in case of repeated dermal contact with styrene. The experiment was carried out in the course of 28 days on 70 albino male rats, treated daily, dermally with 4 ml/kg and 8 ml/kg from the substance and on groups with a following 14--day rehabilitation.