Publications by authors named "V K Sah"
Background: Primary closure of large ventral hernia is difficult and is usually complicated by postoperative mesh bulge, migration, and higher recurrence. Techniques like component separation and bridging mesh, transversus abdominus release, da Silva triple-layer repair, and peritoneal flap hernioplasty (PFH) are common treatment options.
Objective: To evaluate the early postoperative and long-term outcomes of PFH for large ventral hernias.
For the past 3-4 decades, the discovery of Sanger's method of pyrosequencing was the only method unparalleled till 2005 being employed as a method of whole genome sequencing (WGS). Following this, a revolutionary extensive parallel sequencing method, Next Generation Sequencing (NGS), was engineered. NGS supported a substantial number of bases under a high throughput metagenomic interrogation.
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- * This study aimed to improve immunotherapy for UM by identifying specific tumor-reactive T cells in liver metastases using advanced methods like single-cell RNA sequencing and patient-derived xenograft models.
- * The results showed that tumor-reactive T cells were found in both activated and exhausted groups, and insights gained can help enhance cell therapy approaches and identify useful markers for treatment.
Introduction: Totally extraperitoneal (TEP) and transabdominal preperitoneal (TAPP) repair are the principal techniques in laparoscopic hernia repair. Seroma formation and pain are frequent complications of moderate-large size laparoscopic direct inguinal hernia mesh repair. This study was conducted to evaluate the feasibility of defect closure in moderate-large direct inguinal hernias and its effect on various outcomes.
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- This study investigates the differences between brucella spondylodiscitis, an infectious condition, and Modic type I changes (MC1), a non-infectious condition, using hematological inflammatory indices (HII) as potential diagnostic tools.
- A total of 35 patients with brucella spondylodiscitis and 37 with MC1 were analyzed, revealing that while the two groups were similar in various blood parameters, the brucella group had significantly lower pain duration, higher CRP and ESR levels, and lower platelet counts.
- The research found that HII such as neutrophil to lymphocyte ratio showed no significant differences between the groups, suggesting that