Publications by authors named "V K Pruthi"
Artificial photomodulated channels represent a significant advancement toward practical photogated systems because of their remote noncontact stimulation. Ion transport behaviors in artificial photomodulated channels, however, still require further investigation, especially in multiple nanochannels that closely resemble biological structures. Herein, we present the design and development of photoswitchable ion nanochannels inspired by natural channelrhodopsins (ChRs), utilizing photoresponsive polymers grafted anodic aluminum oxide (AAO) membranes.
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- Many fetal anomalies can be diagnosed via ultrasound in early pregnancy, but detection rates are often low; this study focused on using an automated algorithm to identify thickened nuchal translucency (NT), a common indicator of genetic and structural issues in fetuses.
- The researchers collected standardized ultrasound images from 560 fetuses and trained a U-Net convolutional neural network to analyze images, comparing the NT:fetus ratio for effective segmentation and detection of anomalies.
- The study found that the model achieved high accuracy in detecting thick NTs, with a sensitivity of 94% and a specificity of 91%, demonstrating that the algorithm can significantly improve early detection of fetal anomalies, particularly in higher-quality images.
Photoresponsive Spiropyran and DEGMA-Based Copolymers with Photo-Switchable Glass Transition Temperatures.
Macromol Rapid Commun
October 2023
Herein, novel photoresponsive spiropyran (SP)-based P(DEGMA-co-SpMA) copolymers with variable percentages of SP fractions are synthesized. The SP group present in these polymers exhibited the abilities of reversible photoisomerism. Their photoresponsive, structural, and thermal properties have been investigated and compared using various characterization techniques.
View Article and Find Full Text PDFObjective: Ultrasound assessment of the fetal anatomy and fetal echocardiography are feasible in the first trimester of pregnancy. This study was designed to assess the performance of a comprehensive fetal anatomy assessment in a high-risk population at a tertiary fetal medicine unit.
Methods: A retrospective review of high-risk patients undergoing comprehensive fetal anatomy ultrasound assessment between 11 weeks and 13 + 6 weeks of gestation was conducted.
Objective: Pregnancies complicated by fetal heart defects often undergo a planned delivery prior to term by either induction of labour or cesarean delivery to ensure optimal availability of neonatal care. We aimed to assess whether such planned deliveries achieve their goal of better perinatal care.
Methods: We conducted a retrospective case-control study of pregnancies complicated by isolated fetal cardiac defects, without other fetal comorbidities, managed at a single fetal medicine unit over a 10-year period.