[Study of the possibility of hyperparathyroidism development in rats exposed to internal irradiation by iodine radioisotope].

The possibility of hyperparathyroidism development secondary to earlier internal irradiation with radioactive iodine was studied experimentally in Wistar rats. This report describes the parathyroid morphology and biochemical findings for animals irradiated with 131I at the doses of 4.5, 40, or 80 Gy.

[Functional suitability of iodinated casein in the prevention of iodine deficiency].

At least 1.5 billion in the world and over 100 million Russians live in iodine-deficiency areas. The sequelae of this condition are well known.

Prognostic significance of S-phase fraction detected by antithymidine antibodies in epidermoid cervix carcinomas.

Purpose: To assess the predictive value of pretreatment proliferative activity of epidermoid cervix carcinoma cells with respect to short- and long-term results of radiotherapy.

Methods And Materials: The proliferative activity of 25 epidermoid cervix carcinomas was evaluated as the immunofluorescent labeling index (LI) by rabbit antithymidine antibodies reacting specifically with single-stranded DNA of replication forks in S-phase cells. The short-term clinical outcome was estimated at 3-6 months after treatment by visual and palpatory examination.

[The probable sequelae of thyroid damage from radioactive iodine during the Chernobyl accident].

An important peculiarity of the Chernobyl catastrophe is the discharge into the atmosphere of tremendous amount of radioactive iodine and, as a result, selective damage of the thyroid in children from the affected areas. The most dangerous consequence is the thyroid cancer. The analysis of the situation when children's thyroids were subjected to irradiation shows that tumors can most frequently develop as late as 20-30 years after irradiation.

[Anion exchange chromatography of proteins leads to induction of DNA-binding activity in them].

The present work is devoted to investigation of the acquired DNA-binding activity of several proteins, such as bovine serum albumin, myoglobin, and collagens in different conformational states (native, denatured, and gelatin) following their anion exchange chromatography. Induction of DNA-binding activity, as shown, is natural phenomenon common in protein treatment on positively charged matrix. Obviously, anion exchange chromatography of proteins results in their structural conformational changes.