Influence of ion source configuration and its operation parameters on the target sputtering and implantation process.

In the work, investigation of the features and operation regimes of sputter enhanced ion-plasma source are presented. The source is based on the target sputtering with the dense plasma formed in the crossed electric and magnetic fields. It allows operation with noble or reactive gases at low pressure discharge regimes, and, the resulting ion beam is the mixture of ions from the working gas and sputtering target.

Molecular mechanisms of apoptosis.

Apoptosis (Programmed Cell Death) is a genetically regulated, morphologically distinct form of cell death that can be initiated by many different physiological and pathological stimuli. Such strategic intracellular programming is initiated in many instances during normal life cycle and development in order to maintain the homeostasis of a multicellular organism, to eliminate unwanted cells. However, apoptosis is also involved in a wide range of pathologic conditions, including neurodegenerative and cardiovascular diseases, cancer and autoimmune diseases.

[The modifying action of Sophora japonica and an antioxidant vitamin complex on acute radiation injury to the body].

In experiments with mongrel male rats exposed to whole-body gamma-radiation (7, 9 and 11 Gy) the radioprotective effect of enterally administered Sophora japonica and its combination with an antioxidant vitamin complex was investigated. The radioprotective agents applied were shown to produce a synergistic effect.

[Modulating effect of surfactant on protein biosynthesis in lung macrophages].

Effect of lung surfactant on protein biosynthesis in macrophages at their cultivation in vitro has been studied. The surfactant is shown to stimulate protein synthesis in the cells. This phenomenon is probably stipulated by the increase of the transcription activity and formation of 45-pre rRNA, life of RNA.

[Enzyme system of initiation and protection against lipid peroxidation in the liver and blood of rats with hypokinesia].

Content of lipid peroxidation products in liver mitochondria, enzymatic system of the peroxidation initiation (NADPH.H+- and NADH.H+-dependent oxydoreductases) at the early and final steps of liver microsomal redoxchain as well as the activity of protective enzymes superoxide dismutase, ceruloplasmin, catalase and glutathione reductase, preventing the excessive accumulation of lipid peroxidation products in liver mitochondria and erythrocytes were studied in rats with hypokinesia within 1 and 2 months.