[Thromboembolic complications in children].

An analysis was made of 2093 autopsies of children aged 0-14 years. Thromboembolic complications (TEC) were detected in 6.68% of the victims who had died from acute infections, chronic inflammatory diseases, congenital malformations.

[Neuro-ultrasonography in the assessment of perinatal lesions of the brain in high-risk children at birth and at 3 months of age].

As many as 135 children belonging to the group at high risk underwent neurosonography to assess the neuropsychic status in the early neonatal period and at an age of three months. A high rate of perinatal brain injuries was established as was a close relationship between the gestation age of the child, on the one hand and the character and intensity of the injury, on the other one. It has been revealed that the combination of deep immaturity and severe ante-intranatal hypoxia predetermines almost 100% injury of the brain structures, bringing about the formation of organic pathology and impairment of the psychoneurologic development of these children by the age of 3 months.

[Vascular component of the fibrinolytic system of blood (plasminogen activator of vascular wall) in patients with duodenal ulcer with a history of hemorrhagic complications].

It has been established that patients with duodenal ulcer complicated by hemorrhage in the past are characterized by the low response of the fibrinolytic system (FS) to two different exposures--local venous occlusion and administration of the sympathomimetic alupent. The rate of plasminogen the lower limit of normal in almost 2/3 of patients with activator release (RPAR) from vascular depots was under hemorrhages and in 1/4 of those with uncomplicated duodenal ulcer. The low RPAR was coupled with hereditary aggravation and hyperplasia of the parietal glandulocytes of the stomach.

[Changes in the myofibrillary apparatus of the heart in early postnatal ontogenesis of rats in conditions of high altitude and physical exertion].

During postnatal development of rats under high-altitude conditions, the cardiac mass was enlarged as a result of cellular and intracellular hyperplastic processes. Under additional physical exercise the enlargement of the myocardial mass in high-altitude conditions resulted from the hypertrophy of muscle cells, i.e.

[Effect of riboxine on myocardial metabolism in conditions of altitude hypoxia].

Riboxine stimulates activation of redox biosynthetic processes and raises aerobic production of energy in rat myocardium. Under pressure chamber hypoxia corresponding to the altitude 6000 m, riboxine promotes the correction of metabolic acidosis, normalization of the ultrastructure of cardiomyocytes and more balanced development of heart hypertrophy.