Publications by authors named "V K Aravind"

Article Synopsis
  • Klebsiella pneumoniae is a common pathogen in humans with high virulence and antimicrobial resistance, and this study explores its genetic variability across human, animal, and environmental sources.
  • Research involved analyzing K. pneumoniae samples from clinical settings, livestock, and hospital sewage, highlighting significant genetic differences and the abundance of resistance and virulence genes.
  • Findings suggest that the spread of highly resistant K. pneumoniae clones is primarily within human contexts, indicating that these strains likely evolved in hospitals rather than from animals or the environment, challenging current assumptions about AMR transmission.
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Background: Streptococcus dysgalactiae subsp equisimilis (SDSE) is an emerging pathogen causing pharyngitis and post-streptococcal sequelae like S. pyogenes. SDSE was initially considered a commensal microorganism inhabiting the upper respiratory tract and skin.

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Article Synopsis
  • * This study presents a new approach using multimodal wearable sensors and machine learning to assess fatigue levels more accurately, capturing a range of physiological and locomotive signs.
  • * By collecting data from 43 participants in a manufacturing setting, the research showcases an effective multilevel fatigue monitoring system and shares an open-access database for further studies.
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Glioblastoma, which affects a large number of patients every year and has an average overall lifespan of around 14.6 months following diagnosis stands out as the most lethal primary invasive brain tumor. Currently, surgery, radiation, and chemotherapy with temozolomide (TMZ) are the three major clinical treatment approaches.

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An emerging pathotype of Klebsiella pneumoniae, initially identified in Southeast Asian countries, has now spread to multiple countries, including India. These convergent strains, carrying both resistance and virulence determinants, are classified as multidrug-resistant Hypervirulent Klebsiella pneumoniae (MDR-HvKp). Since the initial reports, there has been a concerning surge in infections caused by this pathotype globally.

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