Publications by authors named "V Jorgensen"
Objectives: Assess pateint-reported effects of transcutaneous spinal cord stimulation (tSCS) on spasticity after multiple treatment.
Design: An uncontrolled prospective case series study.
Setting: A rehabilitation hospital.
Article Synopsis
- A study in Denmark focused on patients with COVID-19 associated ARDS who were supported with veno-venous extracorporeal membrane oxygenation (V-V ECMO) to analyze patient selection and outcomes.
- Out of 1,836 ICU patients, 118 were eligible for ECMO, and 71 were cannulated; the median age of patients was 55, with a 90-day mortality rate of 43%.
- Findings indicated that being 60 years or older increased mortality risk while pre-existing hypertension reduced it, aligning with outcomes from similar studies.
Article Synopsis
- Pre-patterning in embryo development is common in non-mammalian species, but mammals were thought to lack this due to their regulative development, which randomly contributes to the three blastocyst lineages.
- Recent studies show that early blastomeres in mouse and human embryos actually have distinct developmental fates and differences in protein levels, challenging the previous notion of randomness.
- Utilizing advanced proteomics, researchers found that 2-cell embryos contain alpha and beta blastomeres with different protein abundances linked to their developmental potential, with beta blastomeres more likely to produce higher amounts of epiblast cells.
In interventional clinical trials for persons with spinal cord injury (SCI), the influence of experimental biological, pharmacological, or device-related interventions must be differentiated from that of physical and occupational therapy interventions, as rehabilitation influences motor-related outcomes. The International Spinal Cord Injury (ISCI) Physical TherapyOccupational Therapy Basic Data Set (PT-OT BDS) was developed with the intent to track the content and time of rehabilitation interventions that are delivered concurrently with experimental interventions. We assessed the reliability of the PT-OT BDS based on agreement between users.
View Article and Find Full Text PDFThe use of prone position ventilation in Danish patients with COVID-19-induced severe acute respiratory distress syndrome treated with veno-venous extracorporeal membrane oxygenation: A nationwide cohort study with focus on pulmonary effects.
Acta Anaesthesiol Scand
October 2024
Background: Prone position ventilation (PPV) is recommended for patients with COVID-19 induced severe Adult Respiratory Distress Syndrome (ARDS) and is used for patients supported with V-V ECMO as well. The purpose of this study was to describe the use of PPV in these patients focusing on physiological effects with the hypothesis that PPV could reduce oxygen need and improve dynamic compliance.
Methods: This study was a nationwide retrospective analysis of all COVID-19 patients in Denmark from March 2020 - December 2021 with severe ARDS and need of V-V ECMO support.