Commercially available tests for determining cefiderocol susceptibility display variable performance in the Achromobacter genus.

Background: Cefiderocol is a siderophore-conjugated cephalosporin increasingly used in the management of Achromobacter infections. Testing for cefiderocol susceptibility is challenging with distinct recommendations depending on the pathogens.

Objectives: We evaluated the performance of commercial tests for testing cefiderocol susceptibility in the Achromobacter genus and reviewed the literature.

Cefiderocol susceptibility of Achromobacter spp.: study of an accurately identified collection of 230 strains.

Background: Achromobacter spp. are opportunistic pathogens, mostly infecting immunocompromised patients and patients with cystic fibrosis (CF) and considered as difficult-to-treat pathogens due to both intrinsic resistance and the possibility of acquired antimicrobial resistance. Species identification remains challenging leading to imprecise descriptions of resistance in each taxon.

Prevalence and variability of siderophore production in the genus.

Unlabelled: spp. are opportunistic pathogens of environmental origin increasingly isolated in patients with underlying conditions like cystic fibrosis (CF). Despite recent advances, their virulence factors remain incompletely studied, and siderophore production has not yet been investigated in this genus.

Impact of population based indoor residual spraying in combination with mass drug administration on malaria incidence and test positivity in a high transmission setting in north eastern Uganda.

Background: Mass drug administration (MDA) and indoor residual spraying (IRS) are potent malaria burden reduction tools. The impact of combining MDA and IRS is not well documented. We evaluated the impact of MDA + IRS compared to IRS alone at a high transmission site in Eastern Uganda.

Biofilm Formation by in the Specific Context of Cystic Fibrosis.

is a major human pathogen whose characteristics support its success in various clinical settings including Cystic Fibrosis (CF). In CF, is indeed the most commonly identified opportunistic pathogen in children and the overall population. colonization/infection, either by methicillin-susceptible or methicillin-resistant strains, will become chronic in about one third of CF patients.