Publications by authors named "V Jariene"
Article Synopsis
- The pilot study investigated how placental mesenchymal stem/stromal cells (MSCs) affect immune cells from patients with hidradenitis suppurativa (HS) by examining peripheral blood mononuclear cells (PBMCs) from both healthy individuals and HS patients.
- PBMCs from HS patients displayed higher levels of the pro-inflammatory cytokines IL-6 and IFN-γ compared to those from healthy subjects, indicating increased inflammation.
- The study found that co-culture with activated MSCs significantly reduced PBMC proliferation and inflammatory cytokine production, suggesting MSCs may have therapeutic potential for HS, although further research with a larger sample size is needed for confirmation.
Article Synopsis
- Atrophic papulosis (Köhlmeier-Degos disease) is a rare vascular condition primarily affecting people aged 20-50 but can occur in children, with a higher male-to-female ratio in pediatric cases.
- A study analyzed data from the Degos Disease Registry, finding that 19 out of 96 patients were children, with median onset age at 5 years, highlighting increased systemic involvement in kids compared to adults.
- Recognizing the specific skin lesions along with neurological or gastrointestinal symptoms is crucial for an accurate diagnosis in pediatric patients, as their presentation may differ from adults.
Atrophic papulosis (Köhlmeier-Degos disease) revisited: a cross-sectional study on 105 patients.
J Eur Acad Dermatol Venereol
November 2022
Background: Atrophic papulosis is a very rare vascular disease of unknown pathogenesis, mostly described by case reports.
Objective: To assess demographic data and prognosis in patients with atrophic papulosis.
Methods: A single-centre study was performed on a series of 105 patients with atrophic papulosis, diagnosed 2000-2021.