Publications by authors named "V J Ruta"
Unlabelled: To date, the percentage composition of the lung microbiome in bronchopulmonary cancer has not been summarized. Existing studies on identifying the lung microbiome in bronchopulmonary cancer through 16S rRNA sequencing have shown variable results regarding the abundance of bacterial taxa.
Objective: To identify the predominant bacterial taxa at the phylum and genus levels in bronchopulmonary cancer using samples collected through bronchoalveolar lavage and to determine a potential proportional pattern that could contribute to the diagnosis of bronchopulmonary cancer.
The conversion of bio-based molecules into valuable chemicals is essential for advancing sustainable processes and addressing global resource challenges. However, conventional catalytic methods often demand harsh conditions and suffer from low product selectivity. This study introduces a series of bifunctional PdPt catalysts supported on TiO, designed for achieving selective and mild-temperature catalysis in biomass conversion.
View Article and Find Full Text PDFSplicing dysregulation: hallmark and therapeutic opportunity in pancreatic cancer.
Trends Mol Med
December 2024
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive cancer characterized by dismal prognosis. Late diagnosis, resistance to chemotherapy, and lack of efficacious targeted therapies render PDAC almost untreatable. Dysregulation of splicing, the process that excises the introns from nascent transcripts, is emerging as a hallmark of PDAC and a possible vulnerability of this devastating cancer.
View Article and Find Full Text PDFArticle Synopsis
- Animals prioritize visual features based on their needs, but less is known about how they adjust their attention as goals change, particularly during social interactions.
- This study focuses on how female Drosophila (fruit flies) modify their visual processing when aggressive, identifying three specific neural circuit motifs that help these flies respond to visual cues related to aggression.
- The research finds that similar neural mechanisms are used in male Drosophila during courtship, highlighting a shared circuitry underlying different social behaviors in these flies.
Article Synopsis
- - Pulmonary fibrosis, particularly idiopathic pulmonary fibrosis (IPF) and secondary pulmonary fibrosis (SPF), is a progressive lung disease that requires accurate differentiation for effective treatment, which this study aims to achieve through various blood-derived ratios and hepatic scores.
- - Conducted at the "Leon Daniello" Clinical Hospital in Romania, the study included 66 patients (38 with IPF and 28 with SPF) to analyze their clinical data and assess the effectiveness of different biomarkers in distinguishing between the two types of pulmonary fibrosis using statistical methods.
- - The results showed that IPF patients had higher FIB-4 scores and RDW/PLT ratios, indicating a greater risk of liver fibrosis, while SPF patients had higher PL