Publications by authors named "V J Ramesh"

Evolutionarily conserved selenoprotein O (SELENOO) catalyzes a post-translational protein modification known as AMPylation that is essential for the oxidative stress response in bacteria and yeast. Given that oxidative stress experienced in the blood limits survival of metastasizing melanoma cells, SELENOO might be able to impact metastatic potential. However, further work is needed to elucidate the substrates and functional relevance of the mammalian homologue of SELENOO.

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Article Synopsis
  • Humans and animals are at risk of avian influenza, which could lead to a pandemic from a new virus that spreads effectively between humans.
  • The study conducted a meta-analysis on three microarray datasets to identify gene expression related to avian influenza, discovering 1,284 common differentially expressed genes.
  • Key findings included important biological pathways related to immune response and specific hub genes, which could provide insights for developing better treatments for the disease.
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