Comparing pregabalin and gabapentin for persistent neuropathic pain: A protocol for a pilot N-of-1 trial series.

Background: Evidence-based management of neuropathic pain is commonly ineffective due to the large variability in response between cases. Patients often have to trial several drugs before finding one that provides adequate relief, leading to increased costs and worsened outcomes. There is thus a need for tools to guide and streamline prescribing decisions in neuropathic pain.

Factors influencing psychological wellbeing of early breast cancer patients.

Aim: This paper aims to identify factors that influence the psychological wellbeing of patients newly diagnosed with localized breast cancer.

Background: Psychological wellbeing plays a significant part in the personal experience of patients during their cancer journey. However, despite progress in treatments and outcomes in breast cancer, psychosocial services and emotional support of cancer patients have been given less attention.

Adherence to guidelines for baseline staging in newly diagnosed localized breast cancer.

Rationale, Aims, And Objectives: Different health agencies in Canada including Cancer Care Ontario (CCO) have developed guidelines for the baseline staging of newly diagnosed breast cancer patients but adherence to them is unknown. We sought to investigate adherence to CCO staging guidelines in a single cancer center in addition to the factors that influence this adherence.

Method: A retrospective chart review was conducted on 212 newly diagnosed breast cancer patients between 2015 and 2017.