Publications by authors named "V Iu Tsytsarev"
Article Synopsis
- Amyloid beta peptides (Aβ) are important markers for Alzheimer's disease and are associated with cognitive decline in Parkinson's disease (PD) and other neurodegenerative conditions.
- The study used a 6-Hydroxydopamine (6-OHDA) model in Wistar rats to investigate Aβ accumulation following dopaminergic cell damage induced by the injection.
- Results indicated a significant increase in Aβ levels at the injection site one hour after the 6-OHDA injection, with a notable presence in blood vessels and possible neuronal cells, linking Aβ accumulation to the progression of PD and its cognitive implications.
Article Synopsis
- Melanin is a diverse and ancient pigment found in many living organisms, serving protective roles like metal chelation and regulating metal concentrations in cells.
- Melanin can acquire magnetic properties by binding with metals, which may influence how organisms respond to magnetic fields.
- This review focuses on the role of melanin in the vertebrate retina, particularly in migratory birds and fish, and explores its possible connections to magnetic sensing.
Dopamine dysfunction (DA) is a hallmark of many neurological disorders. In this case, the mechanism of changes in dopamine transmission on behavior remains unclear. This study is a look into the intricate link between disrupted DA signaling, neuronal activity patterns, and behavioral abnormalities in a hyperdopaminergic animal model.
View Article and Find Full Text PDFMood disorders and substance use disorder (SUD) are of immense medical and social concern. Although significant progress on neuronal involvement in mood and reward circuitries has been achieved, it is only relatively recently that the role of glia in these disorders has attracted attention. Detailed understanding of the glial functions in these devastating diseases could offer novel interventions.
View Article and Find Full Text PDFWe utilize Laser Speckle Contrast Imaging (LSCI) for visualizing cerebral blood flow in mice during and post-cardiac arrest. Analyzing LSCI images, we noted temporal blood flow variations across the brain surface for hours postmortem. Fast Fourier Transform (FFT) analysis depicted blood flow and microcirculation decay post-death.
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