Efficacy of Antiseptic Solutions in Treatment of Infected Surgical Wounds with Patches of Vascular Graft: An Experimental Study in Rats.

Treatment of a prosthetic vascular graft infection (PVGI) remains a challenging problem in vascular surgery. The aim of this study was to design a novel rat model for treatment of peripheral vascular prosthesis infection caused by and to determine the efficacy of different antiseptic solutions in suppressing or eradicating infection from the wound and the graft material itself. A piece of Dacron vascular prosthesis was surgically implanted at the dorsum of 48 Wistar rats and the wounds were infected with 5 McFarland standard inoculum of .

New in vitro model evaluating antiseptics' efficacy in biofilm-associated Staphylococcus aureus prosthetic vascular graft infection.

Purpose: To develop a new in vitro model of prosthetic vascular graft infection (PVGI) and evaluate antimicrobial and biofilm-disrupting efficacy of 0.1% octenidine dihydrochloride, 10% povidone-iodine and 0.02% chlorhexidine digluconate against biofilm-producing Staphylococcus aureus (S.

[Diagnosis of renal vascular disease].

The aim of the study was to assess the diagnostic value of gamma scintigraphy, duplex ultrasound scan, computer tomographic angiography (CTA) and renal arteriography in 77 patients with arterial hypertension, 3 with hematuria, 3 with chronic renal insufficiency and 3 with the difference in kidney size. The following kidney vascularization pathology was revealed: renal artery stenosis in 27, thrombosis of renal artery in 1, aneurysm of renal artery in 4, arteriovenous fistulae in 1, anomalies of renal arteries in 12, atherosclerotic deterioration of accessorial renal arteries in 13, tumor of suprarenal gland with arterial stenosis in 2 patients. Gamma scintigraphy and duplex ultrasound scan were positive in detecting vascular pathology in 93.

Sequential aortofemoropopliteal/distal bypass for treatment of critical lower-limb ischaemia.

Multilevel arterial occlusive disease is often the main cause of critical ischaemia of the lower limb. The aim of this study was to determine the diagnostic criteria that could help select patients for sequential aortofemoropopliteal/distal reconstruction and to compare the results after simultaneous and two-stage surgery. Some 1953 aortofemoral reconstructions were performed during a 6-year period (1987-1992).

Revascularisation of distal tibial and pedal arteries.

The results of 1062 reconstructive operations performed on the tibial and peroneal arteries in patients with Fontaine stage III or stage IV disease are presented. A group of 121 patients in whom the anastomosis was to the tibial or peroneal artery with no direct flow to the foot, and a group of 59 patients with direct anastomoses to the pedal arteries, are analysed in detail.