[Psychological concepts - design of clinical models of schizophrenia].

This publication presents an analysis of the psychological concepts, involved in the construction of clinical models of schizophrenia; in particular - the new clinical-biological paradigm of schizophrenia (reflecting the data of own psychometric studies). Based on the analysis, 3 modes of interaction between clinical and psychological constructs in the construction of models of schizophrenia were identified. The conceptualization of clinical models was carried out from the perspective of the contribution of psychological and psychometric constructs - allowing to expand theoretical ideas about the dynamics of views on the clinical construct of schizophrenia.

[Schizophrenia spectrum disorders (aspects of psychopathology and clinical taxonomy)].

Objective: To create a new taxonomy of schizophrenia spectrum disorders (SSD) based on the comparability of the design of SSD and borderline states.

Material And Methods: The total sample consists of 205 patients with an established diagnosis of SSD (F21; F25; F22 according to ICD-10) collected from studies of the department of borderline mental pathology and psychosomatic disorders of the Federal State Budgetary Institution Mental Health Research Center and the Department of Psychiatry and Psychosomatics of Moscow State Medical University in the period 2014 to 2024. Clinical, psychometric, statistical methods were used.

[Periodic catatonia in schizophrenia spectrum disorders].

Objective: Typological differentiation of periodic catatonia in schizophrenia and schizophrenia spectrum disorders (SSD), in particular, schizoaffective disorder.

Material And Methods: Seventy-four patients with the verified diagnosis of schizophrenia and SSD (ICD-10 items F20, F21) were studied. The clinical, psychometric (BFCRS, SANS) and statistical methods were used.

[Bimodal model of delusional psychoses (on the problem of the correlation of paranoid dimensions in the psychopathological space of schizophrenia)].

Objective: To establish clinico-pathogenetic ratios of delusional psychoses constituting the psychopathological space of paranoid schizophrenia and to determine clinical and pathogenetic validity of concepts of a single delusional psychosis (a model of chronic delusion with a staged course) and two endogenous delusional psychoses.

Material And Methods: A sample consisted of 56 patients (19 women, 37 men; the average age 39.7±9.