Publications by authors named "V Ianole"
Article Synopsis
- Testicular tumors (TTs) in children are uncommon and present unique challenges for diagnosis and treatment; this study examines the role of markers SALL4 and OCT3/4 in understanding these tumors.
- In a review of 18 pediatric cases, SALL4 was found in 83.3% of the tumors, while OCT3/4 was found in 38.9%, with a noted age-related difference in prevalence.
- The research indicates that using SALL4 and OCT3/4 can enhance diagnostic accuracy and treatment strategies, particularly highlighting OCT3/4's potential as a predictive factor for different tumor types and treatment responses.
Atherosclerosis, a leading cause of peripheral artery disease (PAD), is driven by lipid accumulation and chronic inflammation within arterial walls. : This study investigates the expression of ghrelin, an anti-inflammatory peptide hormone, in plaque morphology and inflammation in patients with PAD, highlighting its potential role in age-related vascular diseases and metabolic syndrome. : The analysis specifically focused on the immunohistochemical expression of ghrelin in atherosclerotic plaques and perivascular adipose tissue (PVAT) from 28 PAD patients.
View Article and Find Full Text PDFBackground And Objectives: Although classical gross features are known in hypothermia victims, they lack specific diagnosis features. The aim of our study was to reveal specific brain and lung pathological features in a group of hypothermia-related fatalities.
Materials And Methods: The study group comprised 107 cases from our files associated with hypothermia.
Thyroid collision tumors (TCTs) are rare pathological findings, representing <1% of thyroid cancers. This study aimed to compare the main pathological features of TCTs containing medullary thyroid carcinoma (MTC) and papillary thyroid carcinoma (PTC) components with MTC-only tumors and PTC-only tumors. Methods: The retrospective study included 69 cases diagnosed with TCTs (with simultaneous MTC and PTC components), MTC and PTC.
View Article and Find Full Text PDFArticle Synopsis
- The research aimed to explore the role of Claudin-7, a protein associated with cell junctions, as a potential prognostic biomarker in advanced colorectal carcinoma (CRC) using both statistical methods and AI models.
- Claudin-7 levels were examined in tumors from 84 CRC patients, revealing that higher expression at the invasive front correlated with worse survival outcomes, while expression in the tumor core did not affect prognosis.
- The study concluded that Claudin-7 is a significant prognostic factor in CRC, but AI models failed to predict survival outcomes likely due to the limited patient sample size.