[Antigenic translocation of carcinoembryonic antigen in large intestine epithelial cells].

By an indirect Coons test, a carcinoembryonic antigen (CEA) localization was studied in cells of colon mucosa at various stages of human embryonic development, polyps, and in cases of non-tumoral changes. Laboratory investigations have shown that there are several variants of CEA localization in embryogeny, precancerous tissue, and in cells with inflammatory changes. A comparison of the obtained data and forms of antigenic translocation in malignant tissue leads to a conclusion that the antigenic translocation phenomenon is of biological nature, reflecting the degree of changes in the inner structure of cells under various conditions of existence.

[Pathogenesis of an increased level of carcinoembryonic antigen in the blood in various diseases].

Carcinoembryonic antigen (CEA) was detected in an indirect Coons test in cells of different organs i. e. stomach, esophagus, small intestine, bronchi, trachea, mucosal bronchial glands.

[Antigenic translocation of the "carcinoembryonic antigen" in colonic neoplasms].

The localization of the carcinoembryonic antigen (CEA) in the colon tumours was studied with the indirect Coons test. The localization of CEA in malignant cells was different from that in the normal colon mucosa. In addition, an essential secretion of this antigen may occur in neoplasms.