[Effect of protein C activator on overall haemostasis potential in donor and hip arthroplasty patient plasma].

A method of overall haemostasis potential (OHP) determination for quantitative and rapid estimation of coagulation-fibrinolysis balance in plasma has been presented. The method is based on the analysis of the absorbance at 350 nm vs. time curve, which records the clot formation and dissolution in plasma in the presence of thromboplastin and t-PA.

[Prevention and treatment of posthemorrhagic disorders in surgical treatment of scoliosis].

The measures of the blood loss prophylaxis and compensation, occurred at the time of 4350 surgical interventions on vertebral column conduction in 2697 patients with scoliosis, are analyzed. While performing osteoplastic fixation of vertebral column the blood loss have constituted 1200-2600 ml. The lowering of the blood loss down to 200-120 ml while conducting of complex correcting interventions was permitted by application of the governed hypotension together with general anesthesia.

[Experimental data on the morphogenesis of the spinal compression syndrome in congenital scoliosis].

The authors have made a roentgenologic and histologic study of the preparations of the vertebral columns of 13 rats with congenital scoliosis born to the rats who had been administered a teratogenic drug (6-merkaptopurin) during their pregnancy. In part of the rats the spinal deformations were accompanied by pathologic changes in the vertebrae and in the discs and by an abrupt narrowing (flattening) of the vertebral canal which caused disturbance in the blood flow in the mater spinalis, edema and sclerosis of the epidural space, hypoxia of the neurons, atrophy and glial and cicatrix substitution of the spinal cord tissue in the area of the curvature. The observed clinical picture of the compression spinal syndrome (posterior paraparesis with disturbed functions of the organs of the pelvis) reminded of similar disturbances in the patients with severe congenital kyphoscoliosis.