The observed increase in the production of enzyme preparations (EP) using mutant and genetically modified microorganisms makes it necessary to assess their risks to consumer health. However, at present, their possible influence on the microbiome, immune status of the macroorganism has not been sufficiently studied. of the research was to assess the effect of two EP - the complex of hydrolases with proteolytic and nuclease activity from the Aspergillus oryzae RCAM 01134 mutant strain (EP1) and the neutral protease - bacillolysin and serine protease from the Bacillus subtilis-96 (VKM B-3499D) mutant strain (FP2) on the intestine microbiome and cellular immunity indices of the experimental animals.
View Article and Find Full Text PDFHydrosilanes are widely used as reducing agents in the reduction of carbonyl groups, and various catalysts have been developed for the activation of hydrosilanes, the majority of them being transition metal-based. A main-group-based Lewis acid tris(pentafluorophenyl)borane (BCF) has gained increasing attention due to its Lewis acidity and versatility, along with being nonmetal. Herein, we describe the BCF-catalyzed ring opening reduction of cyclic anhydrides using hydrosilanes as a source of hydrides.
View Article and Find Full Text PDFPolymer research is currently focused on sustainable and degradable polymers which are cheap, easy to synthesize, and environmentally friendly. Silicon-based polymers are thermally stable and can be utilized in various applications, such as columns and coatings. Poly(silyl ether)s (PSEs) are an interesting class of silicon-based polymers that are easily hydrolyzed in either acidic or basic conditions due to the presence of the silyl ether Si-O-C bond.
View Article and Find Full Text PDFDyslipidemias are a risk factor for cardiovascular diseases, especially at a young age. It is known from modern sources that shortchain fatty acids (SCFA) synthesized in the intestine are actively involved in the genesis of dyslipidemia, the spectrum and ratio of which depends on the consumed food substrates. In particular, it has been found that food components such as dietary fiber can affect the lowering of blood lipids by affecting the intestinal microbiota.
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