Publications by authors named "V I Popadyuk"
Article Synopsis
- Rhinosinusitis affects both children and adults, with differences in anatomy, diagnosis, and treatment; adult paranasal sinuses differ significantly from those of children, with adenoids being a major factor in pediatric cases.
- Diagnosis of pediatric rhinosinusitis is challenging due to the rarity of endoscopic examinations and the frequent association with viral infections and chronic adenoiditis.
- DysheLORz, a herbal medicine, has shown effectiveness and safety in treating acute and chronic rhinosinusitis in both age groups, primarily by enhancing immune responses and modulating inflammatory markers.
Expression of the P53 Protein and Morphological Changes in Neurons in the Pyramidal Layer of the Hippocampus After Simulation of Surgical Interventions in the Nasal Cavity in Rats.
Cell Physiol Biochem
February 2023
Background/aims: To determine the role of surgical stress on the formation of p53-positive and dark neurons (DN) in the hippocampus, and to examine the parallelism of their formation in the pyramidal layer of the hippocampus.
Methods: Simulated septoplasty was performed on 20 Wistar rats. The hippocampus and dentate gyrus (DG) were examined, in which the number of DN and p53-positive neurons was determined at 2, 4 and 6 days after surgery.
Article Synopsis
- Chronic rhinitis and chronic rhinosinusitis are linked to sensitization to respiratory allergens, primarily through an IgE-mediated allergic response.
- Accurate diagnosis involves identifying both systemic and local allergic sensitization, which can be determined through skin prick tests, blood tests, and nasal provocation tests.
- Proper evaluation is crucial before diagnosing non-allergic rhinitis to ensure effective management of nasal inflammation and avoid premature conclusions.
The study evaluates the dependence of p53 protein expression on the appearance of dark neurons (DNs) in the hippocampus in rats during experimental modeling of septoplasty. Septoplasty simulation was carried out on 15 sexually mature male Wistar rats. We studied histological sections of the hippocampus stained with Nissl toluidine blue and antibodies to the p53 protein.
View Article and Find Full Text PDFAdenoid hypertrophy (AH) is considered one of the most common diseases in the ear, nose and throat (ENT) practice. The cause of adenoid hypertrophy in children is still unknown. The main aim of the current study was to investigate (interleukin 10) gene polymorphisms and human herpesviruses 6 (HHV6), cytomegalovirus (CMV), and Epstein-Barr virus (EBV) infections in children with AH.
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