[Perspectives and possibilities of luminescent differential diagnosis in endoscopy of stomach ulcers].

On the basis of 1800 examinations of tumor cells the authors show possibility for accumulation of luminescent dye uranine by malignant cells. The conception of the mechanism of its accumulation, confirmed by the studies of reinoculated tumors of rats (60 examinations) is presented. Of 821 patients with ulcers of the stomach 641 had no luminescence; at repeated examination cancer and ulcer were revealed in 7 of them.

Fluorescent diagnostics of human gastric cancer and sodium fluorescein accumulation in experimental gastric cancer in rats.

Patients (459) with chronic gastritis, ulcers, polyposis and different types of gastric cancers were examined by endoscopic fluorescent technique using a special drug based on the sodium salt of fluorescein (F1). Eighty-five percent of gastric cancers showed positive fluorescence. The F1 distribution in the stomach of the rat with induced gastric cancer was examined.

[Use of the fluorescent analysis in early diagnosis of cancer of the stomach].

The effectiveness of a fluorescent analysis in the diagnosis of gastric cancer was studied in 280 patients. Fluorescence of a tumor was noted in 87% of cases. Dependence of fluorescence of a tumor on its sizes was revealed: in tumor diameter less than 1 cm, fluorescence was revealed in 94% of cases, more than 4 cm--in 76%.

[Morphologic evaluation of the potential of fluorescent analysis in the diagnosis of gastric diseases].

A method based on the secondary luminescence of malignant tumours facilitates a more precise taking of biopsies in ulcers and polyps undergoing malignant transformation in carcinoma developing against gastritis background as well as during emergency intraoperative diagnosis. 478 gastroscopies were performed in order to clarify the correlation between fluorescence and the presence of carcinoma in the luminescent biopsies. Biopsies were obtained from both fluorescent and non-fluorescent areas.