On vertebral body growth.

We have studied development of vertebral bodies with special regard to the area of contact of the vertebral body with the intervertebral disc. We have investigated complete serial sections of fetuses of the 2nd to 3rd month of intrauterine life, microscopic preparations from children, adolescents and young adults. The results of our studies and deductions from our findings are as follows: 1.

[Degenerative changes in intervertebral disks].

A histotopographic study of lumbar spine was made in 27 deceased of the age of 2 to 85 years lacking of any spinal clinical symptomatology. Regressive changes were found in all the intervertebral disks except in infants. A central necrosis was present in 26 cases and pericentral striped necrosis in 19 cases.

Radiological picture of juvenile rheumatoid arthritis.

Basing on the results of radiological, clinical and laboratory examinations of 200 children with juvenile rheumatoid arthritis, we tried to obtain a comprehensive picture of radiological changes in the joints, the spine and the remaining skeleton caused by JRA. The bulk of data was obtained in the period between 1954 and 1972, but for some of the patients, our follow-up continued until 1987. Our main interest were differences in morphological changes caused by JRA and adult RA.