[Study of nutritive value of modified casein].

It has been shown that modified casein purified from carbohydrate components contains several times less phosphorus and calcium as compared to initial casein. Figures close to experimental and potential biological value were obtained in experiments on growing rats with modified and initial casein as a protein component-milk substitute.

[The experimental effect of growth stimulants on protein assimilation].

In experiments on rats it was established that the compound CAM-300 in a dose of 2 mg/kg did not induce body mass growth, protein biological value increase or pepsinogen concentration change in the gastric mucosa. Fenobolin stimulation of growth in the experimental animals was attended by a three-fold rise in pepsinogen concentration in the gastric mucosa, the pure utilization of protein being unchanged. The action of the compound 6-(6,10-dioxyundecyl)-beta-resorcin acid gamma-lacton (International Minerals Corporation) did not change biological value and the pure utilization of protein, pepsinogen concentration in the gastric mucosa was slightly lowered.

[Characteristics of proteolysis in the gastrointestinal tract in the early postnatal period].

The activity of proteinases was increased, when we used experimental casein for artificial feeding of newborn rats. Control casein contained in milk substitutes delayed protein evacuation from the stomach. The activity of intestine pancreatic proteinases was increased when we used experimental casein and decreased, for control casein.

[Initial stages of protein assimilation in artificial feeding in an experiment].

The content of pepsinogen in the gastric mucosa and acid phosphatase activity in the gastric chyme are adaptively altered in animals with change from natural to artificial feeding. This change is attended by redistribution of gly-gly-dipeptidase activity along the small intestine. It has been established that fibrinogen and casein are characterized by similar values of the compensation coefficient.