[Rational approaches to selective synthesis of antimetastatic agents].

Some 3,3-dimethyltriazenes were shown to be capable of selective antimetastatic activity, i. e. preventing metastatic spreading of experimental tumors without affecting primary tumor or apparent metastases.

[Hormonal regulation of anabolic processes and the rate of protein utilization in the early postnatal period].

The levels of thyroid, pituitary and corticosteroid hormones--thyroxine, triiodthyronine, 11-oxicorticosteroids in blood serum, somatotropin in pituitary and processes of protein assimilation are studied in rats during early postnatal period. The highest endogen production of thyroxine, triiodthyronine and somatotropin is determined in 15 days old infant rats. The highest levels of protein utilization are determinated in 7-15 days old rats, then the process decreases with going over to definitive nutrition.

[Hormonal regulation of anabolic processes and of protein utilization efficiency in the early postnatal period].

The levels of thyroid, pituitary and steroid hormones-thyroxine, triiodothyronine and 11-hydroxycorticosteroids in the blood serum, somatotropin in the pituitary, and processes of protein assimilation were studied in rats in the early postnatal period. The highest endogenous production of thyroxine, triiodothyronine and somatotropin was detected in 15-day-old rats. The highest level of protein utilization was detected in 7 to 15-day-old rats, followed by the lowering of the utilization on changing over to definitive nutrition.

[Methandrostenolone residues in the tissues and biological fluids of agricultural animals stimulated by the preparation].

Residual amounts of hormonal-active substances were isolated from the tissues of farm animals stimulated with metandrostenolone-3H. The process of isolation included extraction with a mixture of polar solvents, hydrolysis, adsorption and partition column chromatography, thin-layer and paper chromatography, with radio-isotope, fluorometric, spectrophotometric and densitometric methods employed for identification. Results subsequent to determination of residual amounts of the compound are reported.