[Metabolic features of continuous cell lines of mosquitoes].

The metabolism of a continuous Ae. albopictus cell line (clone C6/36) was studied relative to the consumption of an environmental component by mammalian cells of the continuous lines Vero(B) and BNK-21 under steady-state cultivation conditions. The Ae.

[The inhibiting effect of anti-viral chemical substances on a suspended cell culture].

The inhibiting effect of some antiviral drugs on suspension BHK-21 and LECH cell cultures was demonstrated by measuring of the proliferative cytotoxicity and by several changes in cell metabolism. The role of the observed phenomenon in the objective evaluation of the effect of the antiviral drugs in vitro is discussed.

[Index of the proliferative activity of a cell culture in assessing the cytotoxicity of antiviral chemical preparations].

The influence of cytotoxicity of a number of antiviral compounds on the cell culture functional activity was studied by evaluating the changes in the kinetic cell growth parameters. Significant differences between the values of cytotoxicity were found with ribamide in cell lines of different origins. The differences in the measured values of cytotoxicity of the four antiviral compounds under study were demonstrated using the proposed proliferation cytotoxicity criterion (PCT).