[Basis for the use of enclosed 125I sources for interstitial radiation therapy].

Experimental models of closed sources of 125I low energy photon radiation in the titanium capsules sealed by means of pulsed laser welding were designed. Doses in the tissue equivalent medium from a single 125I point source were calculated using ES-1022 computer, tables for calculating dose fields in different layouts of sources were drawn, and layout parameters in preset doses calculated. Using the 125I source in interstitial irradiation of murine breast tumors one managed to establish the local nature of tissues corresponding to the calculated dose distribution for photon radiation with the energy of 27-35 keV.

[Experimental evaluation of Bengal rose labeled with 123I].

Experimental evaluation of Bengal rose labeled with short-lived 123I was performed. The best diagnostic feature in 123I-Bengal rose were shown during a scintigraphic study of the rabbit liver and biliferous tract conducted in simultaneous experiments with the use of the agent labeled with 131I and 99mTc-HIDA. These were a high quality of the image of the organs, a low radiation exposure and the absence of extrahepatic uptake of the agent, particularly under conditions of the ligament of the common bile duct.

[Plastic changes in responses of chemo- and electro-excitable membranes of a cortical neurons following orthodromal tetanization].

Orthodromic tetanization produces in the turtle visual cortex two types of reversible plastic changes of electrical responses: facilitation and depression. Posttetanic facilitation is attended with reversible enhancement of evoked postsynaptic potentials and APs; the excitability of the electroexcitable membrane increases: the critical level of depolarization of the evoked spike shifts in the negative direction and its threshold potential decreases. Posttetanic depression is accompanied by a reversible decrease of the amplitude of evoked postsynaptic and spike potentials; the excitability of the electroexcitable membrane decreases: the critical level of depolarization of the evoked spike shifts in the positive direction, and its threshold potential increases.