Publications by authors named "V I Evstigneev"

Seasonal and interannual dynamics of bioluminescence intensity and succession of the major phytoplankton taxonomic groups were analyzed using the six-year monitoring of Crimean coastal waters (the northern Black Sea) in 2009-2014. Monitoring program included regular CTD and bioluminescence intensity casts in the upper 60 m layer by means of "Salpa-M" sonde accompanied with phytoplankton sampling from subsurface (∼0.2 m) and from the layer of maximal bioluminescence intensity.

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Polymethylmethacrylate (PMMA) is the most commonly used bone void filler in orthopedic surgery. However, the biocompatibility and radiopacity of PMMA are insufficient for such applications. In addition to insufficient biocompatibility, the microbial infection of medical implants is one of the frequent causes of failure in bone reconstruction.

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Large-scale surveys represented by 5800 bathymetric casts in the western Indian Ocean (0-22 N, 54-58 E), elucidated the 10-fold variation of the bioluminescent potential (BP) in the upper mixed layer, during the winter (north-east) monsoon season. The mesoscale survey in February 2017 consisted of 26 drift stations (4 N-3 S, 65-68 E) on which 5-10 bathymetric casts were deployed down to 60 m. The maximal BP was associated with the periphery of a cyclonic eddy.

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The review discusses the theory of interceptor-protector action (the IPA theory) as the new self-consistent biophysical theory establishing a quantitative interrelation between parameters measured in independent physico-chemical experiment and in vitro biological experiment for the class of DNA binding drugs. The elements of the theory provide complete algorithm of analysis, which may potentially be applied to any system of DNA targeting aromatic drugs. Such analytical schemes, apart from extension of current scientific knowledge, are important in the context of rational drug design for managing drug's response by changing the physico-chemical parameters of molecular complexation.

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The present review discusses the current state-of-the-art in building models enabling the description of non-covalent equilibrium complexation of different types of molecules in solution, which results in the formation of supramolecular structures different in length and composition (hetero-association or supramolecular multicomponent co-polymerisation). The description is focused on standard physical and chemical quantities such as experimental observables and equilibrium parameters of interaction (equilibrium constants and concentrations). The major partial cases of the hetero-association models, such as finite and indefinite isodesmic and cooperative complexations, and Benesi-Hildebrand and Langmuir adsorption models are considered.

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