Publications by authors named "V I Bunik"
Article Synopsis
- Recent advances in biology have significantly improved high-throughput analytic methods and genetic techniques.
- These improvements allow for better characterization of the molecular components within living cells.
- Understanding these components and their interactions enhances our knowledge of cellular functions and processes.
Erratum to: Pharmacological Doses of Thiamine Benefit Patients with the Charcot-Marie-Tooth Neuropathy by Changing Thiamine Diphosphate Levels and Affecting Regulation of Thiamine-Dependent Enzymes.
Artem V Artiukhov Olga N Solovjeva Natalia V Balashova Olga P Sidorova Anastasia V Graf Victoria I Bunik
Biochemistry (Mosc)
September 2024
Erratum to: Pharmacological Doses of Thiamine Benefit Patients with the Charcot-Marie-Tooth Neuropathy by Changing Thiamine Diphosphate Levels and Affecting Regulation of Thiamine-Dependent Enzymes.
Artem V Artiukhov Olga N Solovjeva Natalia V Balashova Olga P Sidorova Anastasia V Graf Victoria I Bunik
Biochemistry (Mosc)
August 2024
Pharmacological Doses of Thiamine Benefit Patients with the Charcot-Marie-Tooth Neuropathy by Changing Thiamine Diphosphate Levels and Affecting Regulation of Thiamine-Dependent Enzymes.
Artem V Artiukhov Olga N Solovjeva Natalia V Balashova Olga P Sidorova Anastasia V Graf Victoria I Bunik
Biochemistry (Mosc)
July 2024
Article Synopsis
- - Charcot-Marie-Tooth (CMT) neuropathy is a genetic disorder affecting peripheral nerves, with thiamine (vitamin B1) potentially improving symptoms; this study explores thiamine’s effects when taken daily.
- - Patients showed improved hand grip strength with thiamine and its derivatives (sulbutiamine and benfotiamine), but no significant differences in thiamine-related blood levels were found compared to healthy controls.
- - Interestingly, while thiamine raised grip strength, it also reduced certain enzyme levels (holo-transketolase) in CMT patients, and the way transketolase was activated by thiamine differed between the CMT group and controls, highlighting complex