Publications by authors named "V Huberty"

Article Synopsis
  • - This guideline from ASGE and ESGE outlines evidence-based recommendations about endoscopic bariatric and metabolic therapies (EBMTs) for managing obesity, focusing on their efficacy and safety.
  • - It uses the GRADE framework to assess EBMT devices and procedures that have received CE mark or FDA approval, including those approved within the last five years.
  • - The guidelines recommend EBMTs combined with lifestyle changes for patients with a BMI of ≥30 kg/m² or between 27.0-29.9 kg/m² with at least one obesity-related health issue, specifically suggesting intragastric balloons and endoscopic gastric remodeling devices.
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This joint ASGE-ESGE guideline provides an evidence-based summary and recommendations regarding the role of endoscopic bariatric and metabolic therapies (EBMTs) in the management of obesity. The document was developed using the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) framework. It evaluates the efficacy and safety of EBMT devices and procedures that currently have CE mark or FDA-clearance/approval, or that had been approved within five years of document development.

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Objective: Hemin, a heme oxygenase 1 activator has shown efficacy in the prevention and treatment of acute pancreatitis in mouse models. We conducted a randomized controlled trial (RCT) to assess the protective effect of Hemin administration to prevent post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP) in patients at risk.

Methods: In this multicenter, multinational, placebo-controlled, double-blind RCT, we assigned patients at risk for PEP to receive a single intravenous dose of Hemin (4 mg/kg) or placebo immediately after ERCP.

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Endoscopic therapy is a promising option for patients with gastroesophageal reflux disease (GERD). The aim of this study was to assess safety and feasibility of the Endomina suturing platform as a treatment for GERD. This was a two-center study of patients with chronic GERD symptoms that responded at least partially to proton pump inhibitors (PPIs).

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Obesity is a chronic, relapsing, degenerative, multifactorial disease that is associated with many co-morbidities. The global increasing burden of obesity has led to calls for an urgent need for additional treatment options. Given the rapid expansion of bariatric endoscopy and bariatric surgery across Europe, the European Society of Gastrointestinal Endoscopy (ESGE) has recognized the need to formalize and enhance training in bariatric endoscopy and the endoscopic treatment of bariatric surgical adverse events.

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