Publications by authors named "V Haller"

Purpose: The prognosis of patients with metastatic GIST and imatinib-sensitive primary mutations has significantly improved. However, limited data are available to inform patients about outcomes across different lines of treatment. This retrospective analysis aims to evaluate patient outcomes at a large German GIST referral center over the past 15 years.

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Article Synopsis
  • Coagulopathy and organ dysfunctions are critical features of sepsis, and a study explored the role of tissue factor (TF) and tissue factor pathway inhibitor (TFPI) in septic shock patients.
  • In the study, patients with septic shock had significantly higher levels of both TF and TFPI compared to healthy controls, with differences in their ratios possibly indicating disease severity and outcomes.
  • The research findings suggest that a high TF/TFPI ratio is linked specifically to heart injury in septic patients, while elevated TFPI levels correlate with multiple organ dysfunctions and overall disease severity.
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(1) Background: Autosomal dominant polycystic kidney disease (ADPKD) is a frequent monogenic disorder that leads to progressive renal cyst growth and renal failure. Strategies to inhibit cyst growth in non-human cyst models have often failed in clinical trials. There is a significant need for models that enable studies of human cyst growth and drug trials.

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Background And Aims: Previously, we determined that training with vibrotactile feedback (VTfb) of trunk sway improves MS patients' balance impairment. Here, we posed 5 questions: 1) How many weeks of VTfb training are required to obtain the best short-term carry over effect (CoE) with VTfb? 2) How long does the CoE last once VTfb training terminates? 3) Is the benefit similar for stance and gait? 4) Is position or velocity based VTfb more effective in reducing trunk sway? 5) Do patients' subjective assessments of balance control improve?

Methods: Balance control of 16 MS patients was measured with gyroscopes at the lower trunk. The gyroscopes drove directionally active VTfb in a head-band.

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