Multiple myeloma (MM) is a plasma cell dyscrasia accounting for 10% of all hematologic malignancies. Diagnosis is based on histologic, serologic and radiographic features. The nephrotoxic manifestations of immunoglobulin light chain overproduction are the most common cause of renal function impairment.
View Article and Find Full Text PDFMalignant lymphomas can affect kidneys in several ways. They may precipitate acute renal failure by causing ureteral or renal vascular obstruction, or by direct renal parenchymal infiltration. Furthermore, they may insult renal function via paraneoplastic mechanisms such as hypercalcemia.
View Article and Find Full Text PDFBackground: Persistent secondary hyperparathyroidism not responding to medication is treated successfully with surgical excision of parathyroid glands (total parathyroidectomy [PTX]). PTX without autotransplantation of parathyroid glands excludes the risk for recurrence of hyperparathyroidism.
Methods: During the years 2002 to 2005, 36 total parathyroidectomies were performed in 33 patients: 21 dialysis patients because of end-stage renal disease and 12 renal transplant recipients.