Publications by authors named "V Grossi"

Article Synopsis
  • The study explores the diversity and ecological roles of Woesearchaeota in Lake Dziani Dzaha, revealing their unique genomic features and lifestyles.
  • Researchers identified two distinct populations of Woesearchaeota with a bimodal distribution in depth, linked to different chemical environments, indicating their complex interactions within the microbial community.
  • The findings challenge existing beliefs about the metabolic dependencies of Woesearchaeota, suggesting they exhibit adaptive lifestyles that contribute significantly to ecosystem dynamics.
View Article and Find Full Text PDF

: Hereditary polyposis syndromes are clinically and genetically heterogeneous conditions associated with increased colorectal cancer risk. They are classified based on polyp histology, inheritance mode, causal gene, and colonic and extracolonic manifestations. Their diagnosis is challenging due to overlapping and heterogeneous clinical presentations.

View Article and Find Full Text PDF

Drug resistance is a significant challenge in oncology and is driven by various mechanisms, among which a crucial role is played by enhanced DNA repair. Thus, targeting DNA damage response (DDR) factors with specific inhibitors is emerging as a promising therapeutic strategy. An important process involved in the modulation of DNA repair pathways, and hence in drug resistance, is post-translational modification (PTM).

View Article and Find Full Text PDF

The minor G-allele of FOXO3 rs2802292 is associated with human longevity. The aim of this study was to test the protective effect of the variant against the association with type 2 Diabetes and NAFLD. rs2802292 was genotyped in a large population of middle-aged subjects (n = 650) from a small city in Southern Italy.

View Article and Find Full Text PDF