Publications by authors named "V Gonnier"

Introduction: The elevated rates of neurodevelopmental disorders (NDDs) among siblings of children with autism spectrum disorder (ASD) raise concerns about their developmental monitoring and development. The main aim of this study is to assess the feasibility and acceptability of a standardised screening process on a large sample of siblings.

Methods And Analysis: This prospective study will assess the feasibility of a selective and multi-stage screening process for NDD performed on 384 siblings of children with confirmed ASD.

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Article Synopsis
  • Multimorbidity refers to having multiple chronic health conditions, which is a significant risk factor for poor health and reduced life expectancy, particularly in individuals with autism spectrum disorder and intellectual disability.
  • A preliminary study of 63 adults with autism spectrum disorder and intellectual disability found high rates of multimorbidity and identified four distinct participant classes based on their health conditions, treatments, and independence.
  • The research highlighted a prevalent combination of immune dysfunction, gastrointestinal disorders, and neurological issues, pointing to the need for a tailored approach to improve health outcomes and quality of life for those affected.
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Autism spectrum disorder (ASD) is an early-onset and lifelong neurodevelopmental condition frequently associated with intellectual disability (ID). Although emerging studies suggest that ASD is associated with premature ageing and various medical comorbidities, as described for ID, data are scarce. To determine the comorbidity burden and its association with distinct clinical presentation in terms of ASD severity, adaptive skills, level of autonomy, and drug exposure in a well-phenotyped sample of individuals with ASD-ID-the EFAAR (Frailty Assessment in Ageing Adults with Autism Spectrum and Intellectual Disabilities) cohort.

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The Pervasive Developmental Disorders complications can lead to an important life long handicap. There is an important literature about autism, but in most cases, specifically concerning children and adolescents problems. We wished to focus our attention on adults, in order to describe, on one hand their socio-adaptive profile, and on the other hand, the necessity to resort to a psycho-active treatment.

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Autism is an early developmental disorder. It leads to severe and durable disturbances. Given this problem, no treatment can be excluded a priori.

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