ELEVATED CIRCULATING ENDOTHELIAL CELL-DERIVED MICROVESICLES: A BIOMARKER OF ENDOTHELIAL VASOMOTOR DYSFUNCTION IN ADULTS WITH OBESITY.

Endothelial cell-derived extracellular microvesicles (EMVs) have emerged as a biomarker of cardiovascular disease risk, progression and severity. The aims were to determine: 1) if circulating EMV levels are elevated in adults with obesity; and 2) whether circulating EMVs are associated with obesity-related endothelial vasomotor dysfunction. Thirty-six sedentary, midlife adults (45-63 years) were studied: 18 adults with normal weight (12M/6F; age: 56±6 yr; BMI: 23.

Development of Gelatin-Based Renewable Packaging with Essential Oil for Chicken Breast Preservation.

The aim of this study was to develop gelatin-based films incorporating Melaleuca alternifolia essential oil (MEO) and assess their application on refrigerated chicken breasts. The results showed that MEO exhibited antimicrobial activity against and sp., with inhibition zones of 17 mm and 9 mm, respectively.

Potential of Annatto Seeds ( L.) Extract Together with Pectin-Edible Coatings: Application on Mulberry Fruits ( L.).

L., or mulberry, is a susceptible fleshy fruit due to its high respiratory rate and low storage stability, which shortens its shelf life and makes it difficult to commercialize in natura. Edible coatings, thin membranes produced directly on the desired surface, could improve food preservation, among other properties.

Sex differences in behavioral and neural responses induced by witnessing social defeat stress during adolescence or adulthood in mice.

Psychosocial stress can lead to emotional disorders and memory-related cognitive impairments. Evidence suggests that stress effects vary with age and sex, involving brain structures such as the medial prefrontal cortex (mPFC), amygdala, and hippocampus. This study hypothesized that witnessing social defeat stress (WSDS) during adolescence or adulthood would produce anxiety- and depression-like behaviors and cognitive deficits in adulthood, with outcomes affected by sex.

Electrochemical and Optical Carbon Dots and Glassy Carbon Biosensors: A Review on Their Development and Applications in Early Cancer Detection.

Cancer remains one of the leading causes of mortality worldwide, making early detection a critical factor in improving patient outcomes and survival rates. Developing advanced biosensors is essential for achieving early detection and accurate cancer diagnosis. This review offers a comprehensive overview of the development and application of carbon dots (CDs) and glassy carbon (GC) biosensors for early cancer detection.