Publications by authors named "V Giustolisi"

Rhabdomyolysis is an acute skeletal muscle disorder characterized by altered integrity of the cell membranes of muscle fiber cells. It can be related to a variety of factors: muscular trauma, muscle enzyme deficiencies, infections, drugs, toxins, alcohol ingestion, endocrinopathies and electrolyte imbalances such as hypokalemia. We report the case of a 46-year-old woman admitted to the Emergency Department for frequent episodes of vomiting associated with food intake in the last two weeks, general muscular weakness and myalgia.

View Article and Find Full Text PDF

Metformin is a biguanide commonly used in type 2 diabetes mellitus (DM). Lactic acidosis, a potentially life-threatening metabolic disorder, may be due to a number of different causes, including metformin therapy. We present a case of a severe metformin-induced lactic acidosis in a patient with type 2 DM, admitted to the emergency department with a history of dehydration due to diarrhoea and complicated by acute renal failure.

View Article and Find Full Text PDF

A clinical case of ovarian adenocarcinoma during pregnancy is reported. The diagnostic and therapeutic problems which may be encountered, are illustrated. The data found in the literature concerning ovarian carcinoma in pregnancy are not so many.

View Article and Find Full Text PDF

We describe a case of aplastic anemia with severe thrombocytopenia in a patient affected by chronic active hepatitis C treated with interferon. The hematologic alterations did not disappear after suspension of interferon or after the ensuing steroid treatment. Administration of cyclosporin markedly improved the hematologic parameters and serum transaminase levels.

View Article and Find Full Text PDF