Publications by authors named "V Geist"
Background: Coronary physiology to guide multi-vessel coronary intervention is associated with better outcome. In the presence of a coronary chronic total occlusion (CTO), hemodynamic evaluation of intermediate lesions in the donor coronary artery supplying a CTO territory still has limitations. We aim to evaluate implementing quantitative flow ratio (QFR) in assessing angiographically intermediate lesions of the main donor coronary artery supplying a CTO territory.
View Article and Find Full Text PDFIntroduction: The expansion of transcatheter aortic valve implantation (TAVI) to low-risk and younger patients has increased the relevance of the long-term durability of transcatheter heart valves (THV). The present study aims to assess the 10-year durability, hemodynamic performance, and clinical outcomes after TAVI using the CoreValve system.
Methods: An analysis from a prospective registry with predefined clinical and echocardiographic follow-up included 302 patients who underwent TAVI with the CoreValve system between 2007 and 2015.
Background: In the PREPARE-CALC trial, severely calcified lesion preparation with rotational atherectomy (RA) before biodegradable polymer sirolimus-eluting stent (SES) implantation demonstrated higher procedural success and comparable rates of acute lumen gain and late lumen loss compared to modified balloons (MB) (scoring/cutting). We aimed to analyze the 5-year outcomes of both lesion preparation strategies.
Methods: PREPARE-CALC randomly assigned 200 patients 1:1 to MB or RA, followed by SES implantation.
Article Synopsis
- Interventional left atrial appendage occlusion (LAAO) is effective for patients with nonvalvular atrial fibrillation (AF) who can't use long-term blood thinners, especially those with a history of stroke.
- A study from the LAARGE registry found that LAAO was similarly effective and safe for stroke patients compared to those without a stroke history, with high success rates and low complication rates in both groups.
- The results suggest that LAAO could be a viable option for secondary prevention in high-risk AF patients, showing no significant differences in risk of death or stroke between those with and without prior strokes.
Article Synopsis
- The study examines the prognostic significance of quantitative flow ratio (QFR) measured after successful coronary artery recanalization in predicting target-vessel failure (TVF) compared to the target-vessel SYNTAX score (tvSS).
- Out of 470 chronic total occlusion (CTO) lesions, 324 could be analyzed, revealing that lower post-procedure QFR was associated with a trend toward higher TVF rates, yet it did not significantly predict outcomes.
- In contrast, the pre-procedural tvSS was identified as a significant independent predictor for 2-year TVF, suggesting its importance over immediate QFR assessment for long-term prognosis.