[Evaluation of inhalation toxicity of organic solvent xylene in pregnant rats].

The objective of the present experimental study was the assessment of organism susceptibility to the toxic xylene effect during gestation period, with a view to elaborating recommendations for female work protection. The experiments were carried out in a comparative aspect in 60 pregnant and 60 virgin, sexually matured female albino rats, exposed to 1850 and 467.8 mg/m3 technical xylene in inhalation chambers--levels 40 and 10 times higher than MAC of the solvent, in the course of 21 days (period of gestation of rats), 5 hours daily, 5 times a week.