Preoperative radiotherapy in the combined treatment of lung cancer patients.

The results of a cooperative study on combined treatment and preoperative radiotherapy in 478 lung cancer patients were analyzed. Intensive fractionated radiotherapy was given at doses of 4 Gy for 5 days, the total dosage thus attaining 20 Gy. 218 patients received combined treatment, 260 patients were treated only surgically.

[Use of radiomodifiers during radiotherapy of patients with malignant tumors].

The utilization of various radiomodifiers (hyperbaric oxygenation, metronidazole and their combination, tourniquet and total body gas hypoxia, unconventional dose fractionation) in radiation therapy of over 2000 cancer patients with tumors of the main sites made it possible to raise therapeutic efficacy using a differentiated approach to a choice of therapeutic tactics with relation to radiobiological specificities. The results obtained made it possible to determine the prospects of a further study of the efficacy of the utilization of HBO and MZ and their combination. Tourniquet hypoxia in view of a narrow range of indications and danger of a tumor protection effect should be abandoned.

[Cooperative trials of the Council of Mutual Economic Aid countries on chemoradiotherapy of lung cancer].

The paper is concerned with a comparative analysis of the immediate and short-term results of chemo- and radiotherapy of 174 patients with well differentiated inoperable lung cancer. The data were presented by the participants of the CMEA cooperative trial (the Hungarian People's Republic, the USSR and the Czechoslovak Socialist Republic over the period of 1976-1980). In the course of a randomized study radiotherapy (at a summary dose of 60 Gy) was given to 98 patients, chemotherapy to 76 (methotrexate and 5-fluorouracil).

Results of radiotherapy and combined radiotherapy and chemotherapy of inoperable lung cancer.

In this study there is presented a comparative analysis of immediate results after radiotherapy and combined treatment (radio- and chemotherapy) in 174 patients with highly differentiated inoperable lung cancer. The data were provided by participants of a joint investigation in some CMEA member countries (Hungary, USSR, Czechoslovakia) during the period of 1976 to 1980. In the randomized study radiotherapy (a total dose of 60 Gy) was applied in 98 patients, radiotherapy with chemotherapy (methotrexate and 5-fluorouracil) was applied in 76 patients.