[The influence of aconitum preparations on the development of chronic inflammation].

Experiments show that ethanol extracts prepared from the above-ground parts of Aconitum baicalensis and the above-ground parts and roots of Aconitum septentrionale L. suppressed the exudative and proliferative stages of model chronic inflammation. Both phytopreparations normalized some biochemical indices of the blood (total protein, seromucoids, firbinogen) altered by the inflammation.

Stress-inducing effect of hypoxia of different origin and its correction with Inula Helenium L. tincture.

In order to evaluate the severity of stress, the effects of single and repeated exposure to hypoxia of different origin (hemic, tissue, and circulatory) on the classical parameters of the Selye triad, cytological characteristics of lymphoid organs, and karyometric parameters (nucleus diameters) were studied in all adrenal zones, and analysis of correlations was carried out. The corrective effect of Inula helenium L. tincture manifested in prolongation of the life-span and normalization of somatic and morphological parameters.

[Preclinical toxicologic study of a Baikal aconite tincture (bayacon)].

The safety of bayacon, a new drug based on Baikal aconite intended for the treatment of inflammation-proliferative dermatitis (psoriasis), was studied on a preclinical level. With respect to a single introduction in rats and mice, the drug is classified as a low-toxicity substance. However, a 3-month oral administration of bayacon (0.

[The mechanisms of the anti-ulcer action of plant drug agents].

The mechanisms of the gastroprotective effect of well-known drugs (plantaglucid, befungin, plantain juice), extractions of birch bark (Betula pendula Roth,) and burdock seeds (Arctium tomentosum Mill.) on various links of gastric ulcer pathogenesis were compared. Phytopreparations were found to have a variety of effects on gastric secretion in rats.