Publications by authors named "V G LIAMTSEV"

The study was aim a evaluating effects of intermittent hypoxic training on experimental atherosclerosis. In a three-month experiment rabbits (n = 12) were fed with cholesterol (200 mg/kg of the body mass) and "ascended" to the altitude of 6000 m for 6 hrs per a day. The controls (n = 10) were fed with cholesterol only.

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An analysis was made of 2093 autopsies of children aged 0-14 years. Thromboembolic complications (TEC) were detected in 6.68% of the victims who had died from acute infections, chronic inflammatory diseases, congenital malformations.

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Article Synopsis
  • Acute pressure chamber hypoxia in rats negatively impacts the surfactant system and respiratory structure, leading to reduced surface activity and altered surfactant fluorescence.
  • On the first day, atelectatic foci (collapsed lung areas) are more prevalent than emphysema, but lung structure returns to normal with time.
  • During de-adaptation, surfactant activity and fluorescence levels exceed normal, while the presence of phagocytized surfactant in alveolar macrophages increases, showing a contrasting response to extracellular surfactant changes.
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The superficial activity and cytological composition of bronchoalveolar washes off (BAW) were investigated in 55 patients with bronchial asthma. As compared to the control group the patients with bronchial asthma in remission demonstrated a moderate decrease in the superficial BAW activity which grew in the phase of exacerbation, a degree of variations of the superficial BAW activity depending on the expression of exacerbation. Correlation between a decrease in the superficial BAW activity and changes in an endopulmonary cytogram was found.

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It was shown in rat experiments made with the use of a complex of physical and histological methods and qualitative analysis that changes in the pulmonary surfactant system (PSS) during exposure to altitude chamber hypoxia depend on its duration and intensity. The preliminal effect of hypoxia determines the decrease in PSS activity. The increase in PSS activity seems to be the "emergency compensation" that develops in response to the action of the extreme threshold stimulus.

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