[Medico-biological evaluation of sodium salt of nitrofurylacrylic acid as a food additive].

Nitrofurylacrylic acid sodium salt is a substance of moderate toxicity. Its LD50 for male rats after oral administration comprises 1220 mg/kg, for female rats--1400 mg/kg. The minimal toxic dose, in case of long-term administration comprises 14 mg/kg.

[Experimental study of the possible use of sodium dehydroacetate as a food additive].

The results are presented of toxico-hygienic investigations of dehydroacetic acid sodium salt (DHASS) proposed as a food additive. The compound toxicity values have been assessed, and late results of the preservative influence on the body of experimental animals after its oral intake have been studied. An approximate value of daily intake (AVDI) of the compound has been calculated.

[Harmlessness of plumbagine in a biological experiment].

Plumbagine (2-methyl-5-oxy-1,4-naphtoquinone) did not have any essential effect on the general condition and dynamic changes in the body mass of albino rats, their blood coagulation system and fibrinolysis, the liver and renal functions and morphological structure of the internal organs. An analysis of the available data justify recommending plumbagine as a preservative of soft, when used in doses not exceeding 0.8--1.