Chronic Lymphocytic Leukemia (CLL) is a hematological malignancy marked by the clonal proliferation of the mature, yet dysfunctional B lymphocytes in blood and its subsequent infiltration of the marrow, lymphoid tissues and spleen. The resultant immune dysfunction exposes the body to multiple infections and is a cause of major mortality. Here, we discuss the case of a 46-year-old male suffering from CLL who presented with long-standing episodes of low-grade fever, productive cough and throat irritation, lethargy and pedal edema.
View Article and Find Full Text PDFBreast cancer (BC) ranks number one among cancers affecting women globally. Serious concerns include delayed diagnosis, poor prognosis, and adverse side effects of conventional treatment, leading to residual morbidity. Therefore, an alternative treatment approach that is safe and effective has become the need of the hour.
View Article and Find Full Text PDFPlants have a history of being employed in managing breast cancer. However, no scientific evidence supports the idea that these plants can effectively reduce the level of HER2 expression. In this study, extracts from 10 medicinal plants were evaluated for their anticancer properties against HER2-positive breast cancer cells through various methods, including the SRB assay, comet assay, annexin V-FITC dual staining, and immunoblotting.
View Article and Find Full Text PDFWith a high mortality rate that accounts for millions of cancer-related deaths each year, breast cancer is the second most common malignancy in women. Chemotherapy has significant potential in the prevention and spreading of breast cancer; however, drug resistance often hinders therapy in breast cancer patients. The identification and the use of novel molecular biomarkers, which can predict response to chemotherapy, might lead to tailoring breast cancer treatment.
View Article and Find Full Text PDFBackground And Purpose: Anxiety and fatigue is a common symptom that is seen in cancer survivors, who have recently been diagnosed as well as those who are undergoing chemotherapy and radiation therapy as they are emotionally distressed. Progressive relaxation technique and Benson's relaxation is seen to be efficacious in lowering anxiety and fatigue in cancer survivors as individual treatment. To compare the depiction of progressive relaxation technique and Benson's technique on anxiety using Hamilton anxiety scale (HAM-A), blood pressure (BP) and heart rate (HR), and fatigue using cancer fatigue scale (CFS).
View Article and Find Full Text PDF